510149

tert-Butyl indoline-1-carboxylate

98%

• Synonym(s): N-(tert-Butoxycarbonyl)-2,3-dihydroindole
• Empirical Formula (Hill Notation): C₁₃H₁₇NO₂
• CAS Number: 143262-10-6
• Molecular Weight: 219.28
• MDL number: MFCD01318399
• UNSPSC Code: 12352100
• PubChem Substance ID: 24873481
• NACRES: NA.22

Properties

• assay: 98%
• bp: 83-84 °C/0.1 mmHg (lit.)
• mp: 46-50 °C (lit.)
• SMILES string: CC(C)(C)OC(=O)N1CCc2ccccc12
• InChI: 1S/C13H17NO2/c1-13(2,3)16-12(15)14-9-8-10-6-4-5-7-11(10)14/h4-7H,8-9H2,1-3H3
• InChI key: GWAXLDLPPZPQLO-UHFFFAOYSA-N

Description

General description

tert -Butyl indoline-1-carboxylate is an N-substituted indoline derivative.

Application

• Reactant in preparation of aryl alkyl amines via alkylation reactions catalyzed by Pd
• Reactant in preparation of allyl- and arylindolines
• Reactant in modular indole synthesis of the highly strained CDEF parent tetracycle of nodulisporic acids A and B
• Reactant in asymmetric synthesis of β-amino esters via rhodium prolinate complex-catalyzed α-C-H activation / carbenoid insertion reactions
• Reactant in preparation of substituted indolines and tetrahydroquinolines via cycloaddition approach

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves