490326

(1R,2S)-cis-1,2-Dihydro-1,2-naphthalenediol

0.067 g/mL in 0.1 M phosphate buffer, 98%

• Synonym(s): (1R-cis)-1,2-Dihydro-1,2-naphthalenediol, (1R,2S)-cis-1,2-Dihydro-1,2-dihydroxynaphthalene
• Empirical Formula (Hill Notation): C₁₀H₁₀O₂
• CAS Number: 51268-88-3
• Molecular Weight: 162.19
• Beilstein/REAXYS Number: 1909468
• MDL number: MFCD00216514
• UNSPSC Code: 12352103

Properties

• assay: 98%
• optical activity: [α]22/D +229°, c = 1 in methanol
• concentration: 0.067 g/mL in 0.1 M phosphate buffer
• pH: 8.5(adjusted to)
• mp: 121-127 °C (lit.)
• SMILES string: O[C@H]1C=Cc2ccccc2[C@H]1O
• InChI: 1S/C10H10O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6,9-12H/t9-,10+/m0/s1
• InChI key: QPUHWUSUBHNZCG-VHSXEESVSA-N

Description

Physical form

A suspension in phosphate buffer.

Reconstitution

To recover the pure product from the suspension:
(1)Thaw the frozen suspension and filter the solid. (2) Rinse bottle with a few milliliters of base-washed (aqueous Na₂CO₃) ethyl acetate. (3) Use the rinsing to wash the solid. (4) Collect solid. (5) To further collect more product from the filtrate: extract filtrate with equal volumes of base-washed (aqueous Na₂CO₃) ethyl acetate (repeat three times). (6) Dry the ethyl acetate extract over MgSO₄. (7) Evaporate the solvent - DO NOT HEAT! (8) Combine solids collected from the suspension and the filtrate. Pure crystals should be stored at -78° C. A suspension of the product in phosphate buffer is stable at 0° C.