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483060

Sigma-Aldrich

Sodium dichromate dihydrate

99.995% trace metals basis

Synonym(s):

Sodium bichromate

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About This Item

Linear Formula:
Na2Cr2O7 · 2H2O
CAS Number:
7789-12-0
Molecular Weight:
298.00
EC Number:
234-190-3
MDL number:
MFCD00149166
UNSPSC Code:
12352302
PubChem Substance ID:
24871864

assay

99.995% trace metals basis

form

crystalline

reaction suitability

reagent type: oxidant

mp

91 °C (lit.)

SMILES string

O.O.[Na+].[Na+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O

InChI

1S/2Cr.2Na.2H2O.7O/h;;;;2*1H2;;;;;;;/q;;2*+1;;;;;;;;2*-1

InChI key

JYDRNIYTFCBIFC-UHFFFAOYSA-N

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Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Muta. 1B - Ox. Sol. 2 - Repr. 1B - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Inhalation

Storage Class

5.1B - Oxidizing hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
05914AS

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Isabelle Hininger et al.
Free radical biology & medicine, 42(12), 1759-1765 (2007-05-22)
Several studies have demonstrated beneficial effects of supplemental trivalent Cr in subjects with reduced insulin sensitivity with no documented signs of toxicity. However, recent studies have questioned the safety of supplemental trivalent Cr complexes. The objective of this study was
Chad M Thompson et al.
Toxicological sciences : an official journal of the Society of Toxicology, 123(1), 58-70 (2011-06-30)
Chronic ingestion of high concentrations of hexavalent chromium [Cr(VI)] in drinking water induces intestinal tumors in mice. To investigate the mode of action (MOA) underlying these tumors, a 90-day drinking water study was conducted using similar exposure conditions as in
Chad M Thompson et al.
Regulatory toxicology and pharmacology : RTP, 64(1), 68-76 (2012-06-19)
In vitro studies on hexavalent chromium [Cr(VI)] indicate that reduced forms of this metal can interact with DNA and cause mutations. Recently, Cr(VI) was shown to induce intestinal tumors in mice; however, Cr(VI) elicited redox changes, cytotoxicity and hyperplasia -
Silvio De Flora et al.
Mutation research, 610(1-2), 38-47 (2006-07-29)
Chromium(VI) compounds are genotoxic in a variety of cellular systems. Their potential carcinogenicity is affected by toxicokinetic patterns restricting bioavailability to certain targets, and by metabolic pathways affecting interaction of chromate-derived reactive species with DNA. Epidemiological data indicate that chromium(VI)
Amanda J Lee et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 9(2), 103-115 (2004-09-17)
Hexavalent chromium (Cr[VI]) is a genotoxic carcinogen that has been associated with an increased risk of nasal and respiratory tract cancers following occupational exposure. Although the precise mechanism(s) remain to be elucidated, there is evidence for a role of oxidative
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