471917

3,4-Dichlorophenylboronic acid

≥95%

• Synonym(s): 3,4-Dichlorobenzeneboronic acid
• Linear Formula: Cl₂C₆H₃B(OH)₂
• CAS Number: 151169-75-4
• Molecular Weight: 190.82
• MDL number: MFCD01074646
• UNSPSC Code: 12352103
• PubChem Substance ID: 24870771
• NACRES: NA.22

Properties

• assay: ≥95%
• form: powder
• mp: 280-285 °C (lit.)
• functional group: chloro
• SMILES string: OB(O)c1ccc(Cl)c(Cl)c1
• InChI: 1S/C6H5BCl2O2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,10-11H
• InChI key: JKIGHOARKAIPJI-UHFFFAOYSA-N

Description

Application

Reactant involved in:

• Lithiation/borylation-protodeboronation of homoallyl carbamates
• Suzuki coupling reactions

Precursor / reactant involved in synthesis of biologically active molecules including:

• Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors
• Pyrrole derivatives as PDE4B inhibitors
• Nitrovinyl biphenyls as anticancer agents
• Dual immunosuppressive and anti-inflammatory agents
• Pyrazolopyrimidines as Cryptosporidium and Toxoplasma CDPK1 inhibitors

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves