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441198

Sigma-Aldrich

Boc-L-leucinol

95%

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About This Item

Linear Formula:
(CH3)2CHCH2CH[NHCO2C(CH3)3]CH2OH
CAS Number:
Molecular Weight:
217.31
Beilstein/REAXYS Number:
4178460
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

95%

form

liquid

optical activity

[α]23/D −27°, c = 2 in methanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

application(s)

peptide synthesis

SMILES string

CC(C)C[C@@H](CO)NC(=O)OC(C)(C)C

InChI

1S/C11H23NO3/c1-8(2)6-9(7-13)12-10(14)15-11(3,4)5/h8-9,13H,6-7H2,1-5H3,(H,12,14)/t9-/m0/s1

Inchi Key

LQTMEOSBXTVYRM-VIFPVBQESA-N

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application

Precursor to enantiomerically pure α-methyl amines.[1] Starting material for the synthesis of enantiopure homo-β-amino acids[2][3] and N-protected α-amino aldehydes.[4] Used in the total synthesis of the gastro-protective amicoumacin C.[5]

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Soucek, M. Urban, J.
Collection of Czechoslovak Chemical Communications, 60, 693-693 (1995)
Donner, B.G.
Tetrahedron Letters, 36, 1223-1223 (1995)
R.A. Ward et al.
Tetrahedron, 51, 12301-12301 (1995)
Caputo, R. et al.
Tetrahedron, 51, 12337-12337 (1995)
R. Caputo et al.
Tetrahedron Letters, 36, 167-167 (1995)

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