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437948

Sigma-Aldrich

2-Chloro-1,1,1-trimethoxyethane

97%

Synonym(s):

Trimethyl chloro-orthoacetate

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5 ML
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About This Item

Linear Formula:
ClCH2C(OCH3)3
CAS Number:
74974-54-2
Molecular Weight:
154.59
MDL number:
MFCD00216629
UNSPSC Code:
12352100
PubChem Substance ID:
24867410
NACRES:
NA.22

$83.12

List price$87.50Save 5%
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Available to ship onApril 08, 2025Details

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assay

97%

refractive index

n20/D 1.425 (lit.)

bp

138 °C (lit.)

density

1.147 g/mL at 25 °C (lit.)

functional group

chloro
ether

SMILES string

COC(CCl)(OC)OC

InChI

1S/C5H11ClO3/c1-7-5(4-6,8-2)9-3/h4H2,1-3H3

Inchi Key

NPEIUNVTLXEOLT-UHFFFAOYSA-N

Related Categories

General description

2-Chloro-1,1,1-trimethoxyethane is a chloromethyl heterocyclic compound. It participates in the synthesis of 2-phenyl-1,3,4-oxadiazole derivatives.[1]

Application

2-Chloro-1,1,1-trimethoxyethane may be used for the synthesis of chlorotriazolinone, an NK1 antagonist[2] and 2-chloromethyl-7-[3-(trifluoromethyl)pyridin-2-yl]-3H-quinazolin-4-one.[3]

Pictograms

Flame
GHS02

signalword

Warning

hcodes

H226

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

109.4 °F - closed cup

flash_point_c

43 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM5681
MKCP3656
MKCP3655
MKCP3654
MKCM5682

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