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436089

Sigma-Aldrich

2-Fluoro-6-(trifluoromethyl)benzaldehyde

98%

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About This Item

Linear Formula:
FC6H3(CF3)CHO
CAS Number:
Molecular Weight:
192.11
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

liquid

refractive index

n20/D 1.458 (lit.)

bp

156 °C (lit.)

density

1.432 g/mL at 25 °C (lit.)

SMILES string

Fc1cccc(c1C=O)C(F)(F)F

InChI

1S/C8H4F4O/c9-7-3-1-2-6(5(7)4-13)8(10,11)12/h1-4H

InChI key

FAKUGVHRTLCKHB-UHFFFAOYSA-N

General description

2-Fluoro-6-(trifluoromethyl)benzaldehyde participates in the synthesis of 2-amino-5-trifluoromethylquinazoline.

Application

2-Fluoro-6-(trifluoromethyl)benzaldehyde may be employed for the synthesis of diaryl ether, 2-(3,5-dimethoxyphenoxy)-6-(trifluoromethyl)- benzonitrile and substituted benzo[b]thiophene-2-carboxylates.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

179.6 °F - closed cup

flash_point_c

82 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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Synthesis of Phloroglucinol Monoaryl Ethers.
Sherwood AM, et al.
Synthesis, 44, 1208-1212 (2012)
Synthesis of 2-Aminoquinazolines from ortho-Fluorobenzaldehydes.
Hynes JB and Campbell JP.
Journal of Heterocyclic Chemistry, 34(2), 385-387 (1997)
Tetrahedron Letters, 33, 7499-7499 (1992)

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