412384

PAMAM dendrimer, ethylenediamine core, generation 1.0 solution

20 wt. % in methanol

• Synonym(s): PAMAM dendrimer (G-1)
• Linear Formula: [NH₂(CH₂)₂NH₂]:(G=1);dendri PAMAM(NH₂)₈
• CAS Number: 142986-44-5
• Molecular Weight: 1429.85
• MDL number: MFCD00192448
• UNSPSC Code: 12162002
• PubChem Substance ID: 329756075
• NACRES: NA.23

Properties

• description: amino surface groups
• Quality Level: 100
• form: liquid
• mol wt: generation 1.0
• feature: core type ethylenediamine core (2-carbon core)
• concentration: 20 wt. % in methanol
• no. Surface Groups: 8
• refractive index: n20/D 1.362
• bp: 64.7 °C
• density: 0.82 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: NCCNC(=O)CCN(CCNC(=O)CCN(CCN(CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN
• InChI: 1S/C62H128N26O12/c63-13-21-71-51(89)1-33-83(34-2-52(90)72-22-14-64)45-29-79-59(97)9-41-87(42-10-60(98)80-30-46-84(35-3-53(91)73-23-15-65)36-4-54(92)74-24-16-66)49-50-88(43-11-61(99)81-31-47-85(37-5-55(93)75-25-17-67)38-6-56(94)76-26-18-68)44-12-62(100)82-32-48-86(39-7-57(95)77-27-19-69)40-8-58(96)78-28-20-70/h1-50,63-70H2,(H,71,89)(H,72,90)(H,73,91)(H,74,92)(H,75,93)(H,76,94)(H,77,95)(H,78,96)(H,79,97)(H,80,98)(H,81,99)(H,82,100)
• InChI key: QVWIZHOFYGKROL-UHFFFAOYSA-N

Description

Application

• Gold-Dendrimer Nanocomposites: Study on the synthesis and morphological characterization of gold-dendrimer nanocomposites using PAMAM dendrimers with ethylenediamine cores, evaluating their potential biomedical applications (Vasile, Serafim, Petre, Giol, 2014).
• DNA Interaction Modeling: Analysis of complexes formed between DNA and poly(amido amine) dendrimers of different generations, focusing on modeling DNA wrapping and penetration which includes Generation 1.0 dendrimers (Qamhieh, Nylander, Black, Attard, 2014).

Physical form

Contains 8 surface primary amino groups

Legal Information

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H315,H319,H335,H370
• pcodes: P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1 - STOT SE 3
• target_organs: Eyes,Central nervous system, Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 51.8 °F
• flash_point_c: 11 °C