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411035

Sigma-Aldrich

6-Hydroxyflavone

98%

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About This Item

Empirical Formula (Hill Notation):
C15H10O3
CAS Number:
Molecular Weight:
238.24
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

form

solid

mp

234-236 °C (lit.)

SMILES string

Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3

InChI

1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H

InChI key

GPZYYYGYCRFPBU-UHFFFAOYSA-N

Gene Information

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Structure of 6-hydroxyflavone.
Seetharaman J and Rajan SS.
Acta Crystallographica Section C, Structural Chemistry, 48(9), 1714-1715 (1992)
Xing Wang et al.
PloS one, 10(3), e0116409-e0116409 (2015-03-20)
Inflammatory responses by kidney mesangial cells play a critical role in the glomerulonephritis. The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, tricetin, gossypetin, apigenin and myricetin were investigated on rat mesangial cells with lipopolysaccharide
Zia Ud Din et al.
Histology and histopathology, 35(10), 1197-1209 (2020-09-11)
In this study, the flavonoid, 6-hydroxyflavone was investigated for its renal protective activity in the cisplatin rat model of nephrotoxicity. Male Sprague-Dawley rats weighing 200-250 g were included in the study. 6-Hydroxyflavone was daily administered at 25 and 50 mg/kg
A novel and facile iodine (III)-mediated approach for C (5)-acetoxylation of 6-hydroxyflavone and 6-hydroxyflavanones.
Prakash O, et al.
Tetrahedron Letters, 45(49), 9065-9067 (2004)
Sourav Das et al.
Journal of biomolecular structure & dynamics, 37(15), 4019-4034 (2018-10-14)
The interaction of 6-hydroxyflavone (6HF) with hen egg white lysozyme (HEWL) has been executed using multi-spectroscopic and computational methods. Steady state fluorescence studies indicated that static quenching mechanism is involved in the binding of 6HF with HEWL, which was further

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