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407453

Sigma-Aldrich

(S)-(+)-Norepinephrine L-bitartrate

99%

Synonym(s):

(+)-α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol (+)-tartrate (1:1), D-Noradrenaline L-bitartrate, D-Noradrenaline hydrogen L-tartrate, D-Norepinephrine D-bitartrate

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About This Item

Linear Formula:
(HO)2C6H3CH(CH2NH2)OH · C4H6O6
CAS Number:
Molecular Weight:
319.26
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

assay

99%

optical activity

[α]20/D +38°, c = 1 in H2O

mp

166 °C (dec.) (lit.)

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC[C@@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-;1-,2-/m11/s1

InChI key

WNPNNLQNNJQYFA-HQWYAZORSA-N

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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Wataru Inoue et al.
Nature neuroscience, 16(5), 605-612 (2013-04-09)
Exposure to a stressor sensitizes behavioral and hormonal responses to future stressors. Stress-associated release of noradrenaline enhances the capacity of central synapses to show plasticity (metaplasticity). We found noradrenaline-dependent metaplasticity at GABA synapses in the paraventricular nucleus of the hypothalamus
[Hypovolemic shock during pregnancy].
E M Shifman
Anesteziologiia i reanimatologiia, (6)(6), 63-66 (2013-05-15)
Zhihong Yu et al.
Die Pharmazie, 68(6), 428-430 (2013-07-24)
The aim of this study was to explore the mechanism of domestic beta-aescin treating chronic venous insufficiency through observing its actions on the isolated canine saphenous venous tension, venous pressure, venous return and lymphatic return. The isolated canine spiral saphenous
Anna-Maria Stock et al.
Experimental cell research, 319(12), 1744-1758 (2013-05-04)
We have shown previously that norepinephrine induces migratory activity of tumour cells from breast, colon and prostate tissue via activation of beta-2 adrenergic receptors. Consequently, this effect can be inhibited pharmacologically by clinically established beta-blockers. Tumour cell migration is a
Michiko Nakamura et al.
Journal of neurochemistry, 125(6), 832-842 (2013-04-11)
Histaminergic neurons within the tuberomammillary nucleus (TMN) play an important role in the regulation of sleep-wakefulness. Here, we report the adrenergic modulation of GABAergic transmission in rat TMN histaminergic neurons using a conventional whole-cell patch clamp technique. Norepinephrine (NE) reversibly

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