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Key Documents

403458

Sigma-Aldrich

N-p-Tosylglycine

97%

Synonym(s):

N-(p-Toluenesulfonyl)glycine

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About This Item

Linear Formula:
CH3C6H4SO2NHCH2CO2H
CAS Number:
Molecular Weight:
229.25
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

147-149 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cc1ccc(cc1)S(=O)(=O)NCC(O)=O

InChI

1S/C9H11NO4S/c1-7-2-4-8(5-3-7)15(13,14)10-6-9(11)12/h2-5,10H,6H2,1H3,(H,11,12)

InChI key

VDKFCCZUCXYILI-UHFFFAOYSA-N

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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A Sener et al.
Biochemical pharmacology, 34(14), 2495-2499 (1985-07-15)
N-p-tosylglycine, which inhibits transglutaminase activity in islet homogenates, was found to cause a rapid and sustained facilitation of insulin release evoked by D-glucose, L-leucine or the association of Ba2+ and theophylline in intact islets. Such a facilitating action could not

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