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391395

Sigma-Aldrich

5-Chlorobenzofurazan 3-oxide

97%

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5 G
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Estimated to ship onApril 12, 2025


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5 G
$74.00

About This Item

Empirical Formula (Hill Notation):
C6H3ClN2O2
CAS Number:
Molecular Weight:
170.55
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$74.00


Estimated to ship onApril 12, 2025


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Quality Level

assay

97%

mp

47-48 °C (lit.)

functional group

chloro

SMILES string

[O-][n+]1onc2ccc(Cl)cc12

InChI

1S/C6H3ClN2O2/c7-4-1-2-5-6(3-4)9(10)11-8-5/h1-3H

InChI key

CVHOKJCSOAHYAJ-UHFFFAOYSA-N

General description

5-Chlorobenzofurazan 3-oxide is a benzofuroxan derivative. Its synthesis has been reported.[1]

Application

5-Chlorobenzofurazan 3-oxide (6-Chlorobenzofuroxan) may be used in the synthesis of 3-methyl-2-phenylthioquinoxaline 1,4-dioxide derivative.[1]

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Antonio Carta et al.
European journal of medicinal chemistry, 37(5), 355-366 (2002-05-15)
Thirty-six 6(7)-substituted-3-methyl- or 3-halogenomethyl-2-phenylthio-phenylsulphonyl-chloro-quinoxaline 1,4-dioxides belonging to series 3-6 were synthesised and submitted to a preliminary in vitro evaluation for antimycobacterial, anticandida and antibacterial activities. Antitubercular screening showed a generally good activity of 3-methyl-2-phenylthioquinoxaline 1,4-dioxides (3d,e,h-j) against Mycobacterium tuberculosis, and

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