374237

CHAPSO

95%

• Synonym(s): 3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate
• Empirical Formula (Hill Notation): C₃₂H₅₈N₂O₈S
• CAS Number: 82473-24-3
• Molecular Weight: 630.88
• Beilstein/REAXYS Number: 5842642
• MDL number: MFCD00081079
• UNSPSC Code: 12352103

Properties

• assay: 95%
• optical activity: [α]20/D +19°, c = 2 in H₂O
• mol wt: micellar avg mol wt 7000
• aggregation number: 11
• CMC: 8 mM (20-25°C)
• mp: 184-186 °C (lit.)
• transition temp: cloud point 90 °C
• SMILES string: [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O
• InChI: 1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
• InChI key: GUQQBLRVXOUDTN-XOHPMCGNSA-N

Description

Application

A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.