364517

L-Tryptophan methyl ester hydrochloride

98%, for peptide synthesis

• Synonym(s): (S)-Tryptophan methyl ester hydrochloride, H-(L)-Trp-OMe hydrochloride, L-(-)-Tryptophan methyl ester hydrochloride, Tryptophan methyl ester hydrochloride
• Empirical Formula (Hill Notation): C₁₂H₁₄N₂O₂ · HCl
• CAS Number: 7524-52-9
• Molecular Weight: 254.71
• Beilstein/REAXYS Number: 4240280
• EC Number: 231-385-5
• MDL number: MFCD00066134
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24862436
• NACRES: NA.22

Properties

• product name: L-Tryptophan methyl ester hydrochloride, 98%
• assay: 98%
• optical activity: [α]20/D +18°, c = 5 in methanol
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 218-220 °C (lit.)
• application(s): peptide synthesis
• SMILES string: Cl.COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12
• InChI: 1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H/t10-;/m0./s1
• InChI key: XNFNGGQRDXFYMM-PPHPATTJSA-N

Description

Application

L-Tryptophan methyl ester hydrochloride can be used as a reactant to prepare:

• Oxamoyl derivatives of N-(2-aminobenzoyl)-L-tryptophan (dipeptides) by acylation reaction with 3,1-benzoxazinones.
• Tadalafil (Cialis), a type-V phosphodiesterase (PDE5) inhibitor.
• Isoroquefortine C.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)