357995

Sclareol

98%

• Synonym(s): Labd-14-ene-8,13-diol, (1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol
• Empirical Formula (Hill Notation): C₂₀H₃₆O₂
• CAS Number: 515-03-7
• Molecular Weight: 308.50
• Beilstein/REAXYS Number: 2054148
• EC Number: 208-194-0
• MDL number: MFCD00869558
• UNSPSC Code: 12352002
• PubChem Substance ID: 24861955
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 98%
• optical activity: [α]25/D −13°, c = 4 in carbon tetrachloride
• bp: 218-220 °C/19 mmHg (lit.)
• mp: 95-100 °C (lit.)
• functional group: hydroxyl
• SMILES string: CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@](C)(O)[C@@H]2CC[C@@](C)(O)C=C
• InChI: 1S/C20H36O2/c1-7-18(4,21)13-9-16-19(5)12-8-11-17(2,3)15(19)10-14-20(16,6)22/h7,15-16,21-22H,1,8-14H2,2-6H3/t15-,16+,18-,19-,20+/m0/s1
• InChI key: XVULBTBTFGYVRC-HHUCQEJWSA-N

Description

General description

Sclareol, a diterpene compound with a labdane skeleton, is mainly used as a raw material in the fragrance industry. It shows potent cytotoxic and cytostatic effect in human leukemic cell lines.

Application

Sclareol may be used as a starting material in the synthesis of ambergris fragrance chemicals such as ambraoxide, ambrox, methylambraoxide, ambracetal, ambraketal and epiambraketal. It may also be used in the synthesis of (+)-galanolactone, (-)-8-epi-galanolactone and (+)-labdienedial.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)