35635

cis-3,4-Dichlorocyclobutene

≥95.0% (GC)

• Empirical Formula (Hill Notation): C₄H₄Cl₂
• CAS Number: 2957-95-1
• Molecular Weight: 122.98
• Beilstein/REAXYS Number: 1236770
• EC Number: 220-981-0
• MDL number: MFCD00143990
• UNSPSC Code: 12352100
• PubChem Substance ID: 57649417

Properties

• assay: ≥95.0% (GC)
• refractive index: n20/D 1.503
• bp: 74-76 °C/55 mmHg (lit.)
• density: 1.302 g/mL at 20 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: Cl[C@@H]1C=C[C@@H]1Cl
• InChI: 1S/C4H4Cl2/c5-3-1-2-4(3)6/h1-4H/t3-,4+
• InChI key: MNOAQNJDZROAPA-ZXZARUISSA-N

Description

General description

cis-3,4-Dichlorocyclobutene is a versatile synthon in organic synthesis of natural products.[1] Infrared multiphoton excitation of cis-3,4-dichlorocyclobutene was investigated by optoacoustic detection.[2] cis-3,4-Dichlorocyclobutene undergoes 1,3-dipolar cycloaddition reaction with several nitrile oxides to yield the mixtures of syn- and anti- 4-substituted 6,7-dichloro-2-oxa-3-azabicyclo[3.2.0]hept-3-enes.[3]

Application

cis-3,4-Dichlorocyclobutene may be used in the synthesis of cyclic polyether.[1]

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 131.0 °F - closed cup
• flash_point_c: 55 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter