346292

4,4-Dimethyl-2-phenyl-2-oxazoline

96%

• Empirical Formula (Hill Notation): C₁₁H₁₃NO
• CAS Number: 19312-06-2
• Molecular Weight: 175.23
• MDL number: MFCD00030446
• UNSPSC Code: 12352100
• PubChem Substance ID: 24861389
• NACRES: NA.22

Properties

• assay: 96%
• refractive index: n20/D 1.5322 (lit.)
• bp: 124 °C/20 mmHg (lit.)
• mp: 20-24 °C (lit.)
• density: 1.025 g/mL at 25 °C (lit.)
• SMILES string: CC1(C)COC(=N1)c2ccccc2
• InChI: 1S/C11H13NO/c1-11(2)8-13-10(12-11)9-6-4-3-5-7-9/h3-7H,8H2,1-2H3
• InChI key: UGNSMKDDFAUGFT-UHFFFAOYSA-N

Description

General description

4,4-Dimethyl-2-phenyl-2-oxazoline is an 2-aryl-2-oxazoline and has been tested as as ligand for the Suzuki coupling reaction of aryl bromides and arylboronic acids. 4,4-Dimethyl-2-phenyl-2-oxazoline forms mildly hygroscopic complexes, of general formulae [ZnX₂(ox)₂] (ox =4,4-Dimethyl-2-phenyl-2-oxazoline), with ether solutions of [ZnX₂] (X = Cl, Br, I).Except ZnI₂, which does not form an isolable complex due to steric reasons.

Application

4,4-Dimethyl-2-phenyl-2-oxazoline may be used in the synthesis of an ester-ammonium salt via rupture of oxazoline ring.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 217.4 °F - closed cup
• flash_point_c: 103 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter