343560

Diisopropyl (ethoxycarbonylmethyl)phosphonate

95%

• Synonym(s): Ethyl (diisopropyl phosphono)acetate
• Linear Formula: C₂H₅O₂CCH₂P(O)[OCH(CH₃)₂]₂
• CAS Number: 24074-26-8
• Molecular Weight: 252.24
• MDL number: MFCD00075267
• UNSPSC Code: 12352108
• PubChem Substance ID: 24861175
• NACRES: NA.22

Properties

• assay: 95%
• form: liquid
• reaction suitability: reaction type: C-C Bond Formation
• refractive index: n20/D 1.427 (lit.)
• bp: 142-143 °C/11 mmHg (lit.)
• density: 1.06 g/mL at 25 °C (lit.)
• SMILES string: CCOC(=O)CP(=O)(OC(C)C)OC(C)C
• InChI: 1S/C10H21O5P/c1-6-13-10(11)7-16(12,14-8(2)3)15-9(4)5/h8-9H,6-7H2,1-5H3
• InChI key: YZEWJYIDAAGEHA-UHFFFAOYSA-N

Description

Application

Reactant for:

• Preparation of spiroimine ring fragment of spirolides via stereoselective intermolecular Diels-Alder and aza-Wittig cyclization
• Katsuki-Sharpless epoxidation reaction
• Preparation of nine-membered diallylic sulfonamides as chiral building blocks
• Alpha-phosphono lactams for subsequent Wadsworth-Emmons olefination, and Suzuki coupling reactions to yield diverse pyrrolidinone compounds
• Synthesis of galactosylceramide analog that induces Th1-biased responses in human (NKT) cells
• Stereoselective total synthesis of the ionophore antibiotic zincophorin (M144255)

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves