According to the literature, Rose bengal has been used in a used in neutrophil adherence test and as a generator of singlet oxygen when exposed to laser energy. See: McKinnon, J. , Expt. Med., 164, 1864, (1986) and Gamble and Vadas, Science, 242, 97, (1988).
330000
Rose bengal
≥96% (HPLC), Dye content 95 %
Synonym(s):
4,5,6,7-Tetrachloro-2′,4′,5′,7′-tetraiodofluorescein disodium salt, Acid Red 94, Bengal Rose B sodium salt, Rose Bengal sodium salt
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1 G
$60.50
5 G
$208.00
About This Item
Empirical Formula (Hill Notation):
C20H2Cl4I4Na2O5
CAS Number:
Molecular Weight:
1017.64
Beilstein/REAXYS Number:
3645857
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
Recommended Products
Quality Level
assay
≥96% (HPLC)
form
solid
composition
Dye content, 95%
technique(s)
titration: suitable
color
red to brown
ε (extinction coefficient)
≥ 3000 at 350-354 nm
≥12000 at 311-315 nm
≥32000 at 262-266 nm
≥32000 at 513-517 nm
≥98000 at 546-550 nm at 0.04 g/L (H2O + 1ml 1% Na2CO3)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Na+].[Na+].[O-]C(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C2=C3C=C(I)C(=O)C(I)=C3Oc4c(I)c([O-])c(I)cc24
InChI
1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2
InChI key
UWBXIFCTIZXXLS-UHFFFAOYSA-L
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General description
Rose Bengal is a red or rose color dye and is anionic in nature. It is a 4,5,6,7-tetrachloro 2′,4′,5′,7′-tetraiodo derivative of fluorescein. It is widely used to detect damage to the ocular surface epithelium in ocular surface diseases such as dry eye and herpetic keratitis. Rose Bengal has mild antiviral potency.[1][2]
Rose Bengal is used to stain dead and degenerating cells and mucus.[3]
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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What types of applications can Product 330000, Rose bengal be used for?
1 answer-
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What is the solubility of Rose Bengal, Product 330000?
1 answer-
According to The Sigma-Aldrich Handbook of Stains, Dyes and Indicators, Rose Bengal is soluble in water at 100 mg/mL, ethanol at 30 mg/mL and 2-methoxyethanol at 60 mg/mL. Conn's Biological Stains (10th Edition) states Rose Bengal has a solubility of 36% in water and 8% in ethanol.
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What is the quantum yield of Rose bengal, Product 330000?
1 answer-
According to the literature, the quantum yield of Rose bengal is 0.11. See: Seybold, P.G., et al., Calorimetric, photometric and lifetime determinations of fluorescence yields of fluorescein dyes, Photochem. Photobiol., 9, 229-242 (1969).
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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