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303046

Sigma-Aldrich

2′-Hydroxy-6′-methoxyacetophenone

97%

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About This Item

Linear Formula:
HOC6H3(OCH3)COCH3
CAS Number:
Molecular Weight:
166.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

bp

141 °C/16 mmHg (lit.)

mp

58-60 °C (lit.)

SMILES string

COc1cccc(O)c1C(C)=O

InChI

1S/C9H10O3/c1-6(10)9-7(11)4-3-5-8(9)12-2/h3-5,11H,1-2H3

InChI key

UENLHUMCIOWYQN-UHFFFAOYSA-N

General description

An organometallic synthetic route to 2′-hydroxy-6′-methoxyacetophenone was reported.[1]

Application

2′-Hydroxy-6′-methoxyacetophenone was used as starting material in the synthesis of 5-methoxyflavaone.[2] It was also used in synthesis of 5,6-dihydroxyflavone.[3]

pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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An Organometallic Route to 2'-Hydroxy-6'-methoxy-acetophenone.
Mincheva Z, et al.
Synthetic Communications, 25(2), 149-155 (1995)
204. The synthesis of 5: 6-dihydroxyflavone and the structure of primetin.
Baker W.
Journal of the Chemical Society, 956-961 (1939)
A convenient large-scale synthesis of 5-methoxyflavone and its application to analog preparation
Ares JJ, et al.
The Journal of Organic Chemistry, 58(27), 7903-7905 (1993)

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