Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

295809

Sigma-Aldrich

1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane

≥96%

Synonym(s):

1,10-Diaza-18-crown-6

Sign Into View Organizational & Contract Pricing

Select a Size

1 G
$282.00

$282.00

Available to ship onApril 24, 2025Details

Request a Bulk Order
All Photos(1)

Select a Size

Change View
1 G
$282.00

About This Item

Empirical Formula (Hill Notation):
C12H26N2O4
CAS Number:
23978-55-4
Molecular Weight:
262.35
Beilstein/REAXYS Number:
609764
EC Number:
245-965-0
MDL number:
MFCD00005112
UNSPSC Code:
12352005
PubChem Substance ID:
24857813
NACRES:
NA.22

$282.00

Available to ship onApril 24, 2025Details

Request a Bulk Order

Quality Level

100

assay

≥96%

form

solid

mp

111-114 °C (lit.)

functional group

ether

SMILES string

C1COCCOCCNCCOCCOCCN1

InChI

1S/C12H26N2O4/c1-5-15-9-10-17-7-3-14-4-8-18-12-11-16-6-2-13-1/h13-14H,1-12H2

InChI key

NLMDJJTUQPXZFG-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane is a crown ether, which can be used:
  • In the spectroscopic studies of its complex-forming reaction with iodine.[1]
  • To prepare the ligand 7,16-bis(5-t-butyl-2-hydroxybenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane.[2]
  • As a ligand in the study of zirconium facilitated hydrolysis of a dipeptide at neutral pH.[3]

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBK7543
STBH3751
STBF7412V
STBD8281V
STBC4446V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Spectroscopic studies of the reaction of iodine with the mixed oxygen-nitrogen cyclic base 1, 4, 10, 13-tetraoxa-7, 16-diazacyclooctadecane
Nour E
Spectrochimica Acta Part A: Molecular Spectroscopy, 47(6), 743-747 (1991)
Tuning Zr (IV)-assisted peptide hydrolysis at near-neutral pH
Kassai M and Grant KB
Inorganic Chemistry Communications, 11(5), 521-525 (2008)
Syntheses and crystal structures of copper complexes of 7, 16-bis (5-t-butyl-2-hydroxybenzyl)-1, 4, 10, 13-tetraoxa-7, 16-diazacyclooctadecane
Ma S, et al.
Polyhedron, 22(25-26), 3249-3253 (2003)
L P Varga et al.
International journal of radiation biology, 66(4), 399-405 (1994-10-01)
To date, there has been no effective therapy to counter incorporated radionuclides of strontium. In an endeavour to solve this problem, we have synthesized and evaluated various N,N'-disubstituted derivatives of 1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane(crypt and 2.2) for their ability to mobilize 85Sr2+. These
Fran Supek et al.
European journal of medicinal chemistry, 46(8), 3444-3454 (2011-06-02)
18-crown-6 ethers are known to exert their biological activity by transporting K(+) ions across cell membranes. Using non-linear Support Vector Machines regression, we searched for structural features that influence antiproliferative activity in a diverse set of 19 known oxa-, monoaza-

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service