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286192

4-Pregnen-20α-ol-3-one

Synonym(s):

20α-Hydroxy-4-pregnen-3-one, 20α-Hydroxyprogesterone

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About This Item

Empirical Formula (Hill Notation):
C21H32O2
CAS Number:
145-14-2
Molecular Weight:
316.48
EC Number:
205-649-5
MDL number:
MFCD00009823
UNSPSC Code:
12352200

SMILES string

C[C@H](O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RWBRUCCWZPSBFC-RXRZZTMXSA-N

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pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
82560KM

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Martha Lappas et al.
The Journal of endocrinology, 186(3), 457-465 (2005-09-02)
The aim of this study was to determine the release and regulation of leptin, resistin and adiponectin from human placenta and fetal membranes, and maternal subcutaneous adipose tissue and skeletal muscle obtained from normal and gestational diabetes mellitus (GDM)-complicated pregnancies
C Longcope et al.
Maturitas, 8(3), 189-196 (1986-10-01)
We obtained blood samples from 88 women 45-58 yr old who were having cyclic menses every 1-2 mth (37 women, 133 samples) or were amenorrheic for greater than 3 mth (51 women, 310 samples). Samples were obtained at intervals of
A Reinberg et al.
Fertility and sterility, 49(2), 309-315 (1988-02-01)
Prevasectomy levels of plasma luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone (T), estradiol (E2), and 20 alpha-dihydroprogesterone (20 alpha-DHP), as well as semen analyses including semen volume, sperm count, and sperm motility from 260 healthy men were evaluated for annual
M L Casey et al.
The Journal of clinical investigation, 70(2), 312-319 (1982-08-01)
In this investigation we found that little of intravenously infused [14C]deoxycorticosterone (DOC) was converted to [14C]DOC-SO4 that entered plasma. Moreover little of intravenously infused [3H]DOC-SO4 was metabolized by way of DOC except by intestinal bacterial enzymes. However evidence was obtained
Nina S Stachenfeld et al.
Journal of applied physiology (Bethesda, Md. : 1985), 98(6), 1991-1997 (2005-02-19)
Adequate plasma volume (PV) and extracellular fluid (ECF) volume are essential for blood pressure and fluid regulation. We tested the hypotheses that combined progesterone (P(4))-estrogen (E(2)) administration would increase ECF volume with proportional increases in PV, but that P(4) would
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