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Key Documents

272930

Sigma-Aldrich

4-(Benzyloxy)phenol

≥99%

Synonym(s):

4-(Phenylmethoxy)phenol, Hydroquinone monobenzyl ether

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About This Item

Linear Formula:
C6H5CH2OC6H4OH
CAS Number:
Molecular Weight:
200.23
Beilstein/REAXYS Number:
1958305
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

≥99%

mp

119-120 °C (lit.)

SMILES string

Oc1ccc(OCc2ccccc2)cc1

InChI

1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2

InChI key

VYQNWZOUAUKGHI-UHFFFAOYSA-N

Gene Information

human ... TYR(7299)
rat ... Ar(24208)

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Description
Pricing

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Jasper G van den Boorn et al.
The Journal of investigative dermatology, 131(6), 1240-1251 (2011-02-18)
In this study, we report the previously unknown mechanism of inducing robust anti-melanoma immunity by the vitiligo-inducing compound monobenzone. We show monobenzone to increase melanocyte and melanoma cell immunogenicity by forming quinone-haptens to the tyrosinase protein and by inducing the
Hearing aid depigmentation.
A K Bajaj et al.
Contact dermatitis, 27(2), 126-127 (1992-08-01)
Jasper G van den Boorn et al.
PloS one, 5(5), e10626-e10626 (2010-05-26)
Presently melanoma still lacks adequate treatment options for metastatic disease. While melanoma is exceptionally challenging to standard regimens, it is suited for treatment with immunotherapy based on its immunogenicity. Since treatment-related skin depigmentation is considered a favourable prognostic sign during
M D Njoo et al.
Archives of dermatology, 135(12), 1514-1521 (1999-12-22)
To develop and introduce evidence-based guidelines for the treatment of vitiligo in children and in adults. Patients, residents, and dermatologists from the Department of Dermatology, Academic Medical Center, University of Amsterdam, and the Netherlands Institute for Pigmentary Disorders in Amsterdam.
Contact hypersensitivity to monobenzyl ether of hydroquinone used to treat vitiligo.
C C Lyon et al.
Contact dermatitis, 39(3), 132-133 (1998-10-15)

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