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Key Documents

254819

Sigma-Aldrich

Hydroquinidine hydrochloride

98%

Synonym(s):

Dihydroquinidine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H26N2O2 · HCl
CAS Number:
Molecular Weight:
362.89
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

powder

optical activity

[α]20/D +185.2°, c = 1.3 in H2O

mp

277-279 °C (lit.)

functional group

hydroxyl

SMILES string

Cl.CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c3ccnc4ccc(OC)cc34

InChI

1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1

InChI key

MULXTQKDWYBJMO-VJAUXQICSA-N

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Saleem Aladaileh et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 148(4), 470-480 (2007-10-24)
Phenoloxidase (PO) activity was studied in Sydney rock oysters (Saccostrea glomerata). As in other molluscs, PO was found to exist as a pro-enzyme (proPO) in hemocytes. ProPO could be activated to PO by exogenous proteases (trypsin and chymotrypsin), exposure of
Fiorenzo Gaita et al.
Journal of the American College of Cardiology, 43(8), 1494-1499 (2004-04-20)
The purpose of this study was to evaluate the efficacy of various antiarrhythmic drugs at prolonging the QT interval into the normal range and preventing ventricular arrhythmias in patients with short QT syndrome. Short QT syndrome is a recently described
Ad Kane et al.
Annales de cardiologie et d'angeiologie, 61(4), 292-295 (2011-06-15)
A 45-year-old man was hospitalized for syncope due to fascicular ventricular tachycardia degenerating into ventricular fibrillation (VF). The electrocardiogram showed an early repolarization syndrome. The arrhythmia was repetitive and disappeared after oral hydroquinidine. An implantable cardioverter-defibrillator (ICD) was implanted; subsequently
Arti T Navare et al.
Journal of mass spectrometry : JMS, 45(6), 635-642 (2010-06-09)
Atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI) is known to suffer from poor ion transfer efficiencies as compared to conventional vacuum MALDI (vMALDI). To mitigate these issues, a new AP-MALDI ion source utilizing a coaxial gas flow was developed. Nitrogen
Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant.
Elisa Pirro et al.
British journal of clinical pharmacology, 72(6), 982-984 (2011-06-29)

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