Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

253367

Sigma-Aldrich

4-(2-Iodoacetamido)-TEMPO

free radical

Synonym(s):

4-(2-Iodoacetamido)-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical, 4-(2-Iodoacetamido)-2,2,6,6-tetramethylpiperidine 1-oxyl

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C11H20IN2O2
CAS Number:
25713-24-0
Molecular Weight:
339.19
MDL number:
MFCD00010171
UNSPSC Code:
12352101
PubChem Substance ID:
24855308
NACRES:
NA.22

form

solid

mp

114-117 °C (lit.)

functional group

amide
iodo

storage temp.

2-8°C

SMILES string

CC1(C)CC(CC(C)(C)N1[O])NC(=O)CI

InChI

1S/C11H20IN2O2/c1-10(2)5-8(13-9(15)7-12)6-11(3,4)14(10)16/h8H,5-7H2,1-4H3,(H,13,15)

InChI key

UCTVRHAKQRFPEZ-UHFFFAOYSA-N

Application

Methionine-specific spin label.[1]
Spin label used to investigate the binding site of phosphoenolpyruvate caboxykinase and GTP, and to evaluate the alkylation of SH1 and SH2 of myosin.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
07124CZ
12409MS

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

4-Oxo-TEMPO

Sigma-Aldrich

179485

4-Oxo-TEMPO

TEMPO 98%

Sigma-Aldrich

214000

TEMPO

C Wells et al.
Journal of muscle research and cell motility, 5(1), 97-112 (1984-02-01)
The properties of spin-labelled myosin, prepared from rabbit skeletal and scallop adductor muscle, on forming a long-lived complex with ADP and vanadate (M.ADP.Vi), have been investigated. In the case of an iodoacetamide-based label attached to rabbit myosin or subfragment 1
C Coan et al.
Biochemistry, 21(13), 3214-3220 (1982-06-22)
The labeling kinetics of sarcoplasmic reticulum ATPase with the iodoacetamide spin probe N-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide were followed under conditions designed to selectively label all reactive groups. Approximately 1 mol of spin-label reacted per one 100 000-dalton ATPase chain, indicating only one residue
E Gendek et al.
British journal of industrial medicine, 41(1), 46-50 (1984-02-01)
Alterations in erythrocyte membranes caused by UICC B chrysotile asbestos fibres were studied in red cell ghosts using the spin label technique. The electron paramagnetic resonance (EPR) spectra of two sulphydryl reactive spin labels and one fatty acid spin probe
J Gollub et al.
Biochemistry, 38(31), 10107-10118 (1999-08-06)
We have observed the effects of MgADP and thiophosphorylation on the conformational state of the light chain domain of myosin in skinned smooth muscle. Electron paramagnetic resonance (EPR) spectroscopy was used to monitor the orientation of spin probes attached to
A Wawrzynow et al.
Biochemistry, 32(40), 10803-10811 (1993-10-12)
Sarcoplasmic reticulum vesicles were labeled with [14C]iodoacetamide spin-label (ISL) under conditions where time courses of the reaction predicted that one amino acid residue would be preferentially labeled. Solubilized tryptic peptides were separated by high-performance liquid chromatography following extensive digestion, and
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service