24377

2-Chloro-1,3-dimethylimidazolidinium tetrafluoroborate

≥95.0% (AT)

• Synonym(s): CIB
• Empirical Formula (Hill Notation): C₅H₁₀BClF₄N₂
• CAS Number: 153433-26-2
• Molecular Weight: 220.40
• MDL number: MFCD09039291
• UNSPSC Code: 12352005
• PubChem Substance ID: 57648080
• NACRES: NA.22

Properties

• assay: ≥95.0% (AT)
• form: solid
• reaction suitability: reaction type: Coupling Reactions
• mp: 175-177 °C (lit.); 175-178 °C
• solubility: acetonitrile: 0.1 g/mL, clear
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: F[B-](F)(F)F.CN1CC[N+](C)=C1Cl
• InChI: 1S/C5H10ClN2.BF4/c1-7-3-4-8(2)5(7)6;2-1(3,4)5/h3-4H2,1-2H3;/q+1;-1
• InChI key: UPLXKEIRISBKRM-UHFFFAOYSA-N

Description

Application

Reagent for:
Esterification and peptide coupling of sterically hindered amino acids
Preparation of efficient diazo-transfer reagents
Oxidative insertion for palladium and nickel catalyst synthesis
Preparation of catalysts for use in coupling reactions

Other Notes

Reagent for esterification of C-terminal amino acids to Wang resin without racemization and for coupling α,α-dimethyl amino acids; Preparation of the benzotriazol-1-yloxy derivative, a new coupling reagent

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves