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Key Documents

240699

Sigma-Aldrich

Epichlorohydrin

≥99%

Synonym(s):

(±)-Epichlorohydrin, (±)-2-(Chloromethyl)oxirane, 1-Chloro-2,3-epoxypropane

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About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
Molecular Weight:
92.52
Beilstein/REAXYS Number:
79785
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

vapor density

3.2 (vs air)

vapor pressure

13.8 mmHg ( 21.1 °C)

assay

≥99%

autoignition temp.

779 °F

expl. lim.

21 %

refractive index

n20/D 1.438 (lit.)

bp

115-117 °C (lit.)

mp

−57 °C (lit.)

density

1.183 g/mL at 25 °C (lit.)

SMILES string

ClCC1CO1

InChI

1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2

Inchi Key

BRLQWZUYTZBJKN-UHFFFAOYSA-N

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Application

Employed in the preparation of polyglycidyl ethers and as a cross-linking agent for polymers.
Used in the synthesis of a branched heptaglycerol dendrimer.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

82.4 °F

flash_point_c

28 °C


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Synthesis, 487-487 (1993)
Chromatographia, 37, 603-603 (1993)
Synlett, 2091-2091 (2007)
An evaluation of the genetic toxicity of epichlorohydrin. A report of an expert group of the International Commission for Protection against Environmental Mutagens and Carcinogens.
R J Srám et al.
Mutation research, 87(3), 299-319 (1981-11-01)
Swetha Inturi et al.
ACS nano, 9(11), 10758-10768 (2015-10-22)
Notwithstanding rapid advances of nanotechnology in diagnostic imaging and drug delivery, the engineered nanocarriers still exhibit substantial lack of hemocompatibility. Thus, when injected systemically, nanoparticles are avidly recognized by blood leukocytes and platelets, but the mechanisms of immune recognition are

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