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Key Documents

238201

Sigma-Aldrich

4-Nitrophthalic anhydride

92%

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About This Item

Empirical Formula (Hill Notation):
C8H3NO5
CAS Number:
Molecular Weight:
193.11
Beilstein/REAXYS Number:
179682
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

assay

92%

impurities

5-8% 3-nitrophthalic anhydride

mp

116-120 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc2C(=O)OC(=O)c2c1

InChI

1S/C8H3NO5/c10-7-5-2-1-4(9(12)13)3-6(5)8(11)14-7/h1-3H

InChI key

MMVIDXVHQANYAE-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Nasimossadat Banarouei et al.
Mini reviews in medicinal chemistry, 19(8), 679-687 (2018-04-26)
N-aryl derivatives of phthalimide and 4-nitro phthalimide have demonstrated cyclooxygenase inhibitory activity. Also, they possess excellent analgesic and antiinflammatory activity. In this work, a new series of N-arylmethylideneamino derivatives of phthalimide and 4-nitro phthalimide were designed and synthesized. The designed
Vu H Nguyen et al.
EJNMMI research, 3(1), 80-80 (2013-12-18)
Sigma2 (σ2) receptors are highly expressed in cancer cell lines and in tumours. Two novel selective 18F-phthalimido σ2 ligands, 18F-SIG343 and 18F-SIG353, were prepared and characterised for their potential tumour imaging properties. Preparation of 18F-SIG343 and 18F-SIG353 was achieved via
Kalyan K Sethi et al.
Pharmaceuticals (Basel, Switzerland), 14(7) (2021-08-07)
New derivatives were synthesised by reaction of amino-containing aromatic sulphonamides with mono-, bi-, and tricyclic anhydrides. These sulphonamides were investigated as human carbonic anhydrases (hCAs, EC 4.2.1.1) I, II, IX, and XII inhibitors. hCA I was inhibited with inhibition constants

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