221058

Tris(dimethylamino)methane

97%

• Linear Formula: [(CH₃)₂N]₃CH
• CAS Number: 5762-56-1
• Molecular Weight: 145.25
• Beilstein/REAXYS Number: 1901162
• EC Number: 227-284-0
• MDL number: MFCD00008322
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853207
• NACRES: NA.22

Properties

• assay: 97%
• form: liquid
• refractive index: n20/D 1.436 (lit.)
• bp: 42-43 °C/12 mmHg (lit.)
• density: 0.838 g/mL at 20 °C (lit.)
• functional group: amine
• storage temp.: 2-8°C
• SMILES string: CN(C)C(N(C)C)N(C)C
• InChI: 1S/C7H19N3/c1-8(2)7(9(3)4)10(5)6/h7H,1-6H3
• InChI key: MUMVIYLVHVCYGI-UHFFFAOYSA-N

Description

General description

NMR spectra and their temperature-dependence has been reported for tris(dimethylamino)methane. Tris(dimethylamino)methane reacts with crowded α-(o-nitrophenyl) ketone to yield tetrahydroquinoline derivative.

Application

Tris(dimethylamino)methane was used:

• to prepare the phosphoramidite derivative of the new nucleoside analog
• as reagent for the introduction of the dimethylaminoethylidene group
• in ring-opening (RO) polymerization of lactide

Safety Information

• pictograms: GHS02,GHS05
• signalword: Danger
• hcodes: H225,H314
• pcodes: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Flam. Liq. 2 - Skin Corr. 1B
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 51.8 °F - closed cup
• flash_point_c: 11 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter