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220493

Sigma-Aldrich

Mersalyl acid

97%

Synonym(s):

2-(3-Hydroxymercurio-2-methoxypropylcarbamoyl)phenoxyacetic acid, 2-[N-(3-Hydroxymercuri-2-methoxypropyl)carbamoyl]phenoxyacetic acid, Salyrganic acid

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About This Item

Linear Formula:
HOHgCH2CH(OCH3)CH2NHCOC6H4OCH2CO2H
CAS Number:
Molecular Weight:
483.87
EC Number:
MDL number:
UNSPSC Code:
12352103

assay

97%

mp

192-193 °C (dec.) (lit.)

SMILES string

COC(CNC(=O)c1ccccc1OCC(O)=O)C[Hg]O

InChI

1S/C13H16NO5.Hg.H2O/c1-9(18-2)7-14-13(17)10-5-3-4-6-11(10)19-8-12(15)16;;/h3-6,9H,1,7-8H2,2H3,(H,14,17)(H,15,16);;1H2/q;+1;/p-1

InChI key

HQRSUIDICNOLPX-UHFFFAOYSA-M

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Jason M Gooding et al.
European journal of biochemistry, 271(5), 954-961 (2004-03-11)
Recent studies have suggested that parts of the hepatic activities of diacylglycerol acyltransferase and acyl cholesterol acyltransferase are expressed in the lumen of the endoplasmic reticulum (ER). However the ER membrane is impermeable to the long-chain fatty acyl-CoA substrates of
Manuel Gutiérrez-Aguilar et al.
Archives of biochemistry and biophysics, 494(2), 184-191 (2009-12-10)
The mitochondrial permeability transition (PT) involves the opening of a mitochondrial unselective channel (MUC) resulting in membrane depolarization and increased permeability to ions. PT has been observed in many, but not all eukaryotic species. In some species, PT has been
G Moreno et al.
Archives of biochemistry and biophysics, 386(2), 243-250 (2001-05-23)
We have examined whether the effects of singlet oxygen (1O2) produced by photodynamic action on the mitochondrial permeability transition (PT) can be modulated by the localization of photosensitizers in irradiated mitochondria. We have previously shown that oxidation due to 1O2
F Agani et al.
Molecular pharmacology, 54(5), 749-754 (1998-11-06)
In response to hypoxia, mammalian cells express multiple gene products [including erythropoietin (EPO) and vascular endothelial growth factor (VEGF)] that serve to increase O2 delivery, as well as glucose transporters and glycolytic enzymes (such as enolase 1) that allow metabolic
Maura Nicoletta Laus et al.
Plant & cell physiology, 49(7), 1039-1055 (2008-05-31)
To date, the existence of the plant inner membrane anion channel (PIMAC) has been shown only in potato mitochondria, but its physiological role remains unclear. In this study, by means of swelling experiments in K(+) and ammonium salts, we characterize

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