Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

205206

Sigma-Aldrich

2-Amino-5-bromo-6-methyl-4-pyrimidinol

97%

Synonym(s):

5-Bromo-6-methylisocytosine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C5H6BrN3O
CAS Number:
6307-35-3
Molecular Weight:
204.02
EC Number:
228-623-5
MDL number:
MFCD00006092
UNSPSC Code:
12352100
PubChem Substance ID:
24852312
NACRES:
NA.22

assay

97%

mp

244-246 °C (lit.)

functional group

bromo

SMILES string

Cc1nc(N)nc(O)c1Br

InChI

1S/C5H6BrN3O/c1-2-3(6)4(10)9-5(7)8-2/h1H3,(H3,7,8,9,10)

InChI key

ADLWOFHKMXUDKF-UHFFFAOYSA-N

General description

2-Amino-5-bromo-6-methyl-4-pyrimidinol induced high levels of serum interferon in mice.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
03496LJV
03496LJ
07422CH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

D A Stringfellow et al.
Journal of interferon research, 1(1), 1-14 (1980-01-01)
The interferon inducing characteristics of a new series of 6-phenyl pyrimidinol compounds are described and compared against a previously identified pyrimidine, 2-amino-5-bromo-6-methyl-4-pyrimidinol (ABMP). Interestingly, a split in ability to induce interferon but not in vivo antiviral activity was observed in
D A Stringfellow
Antimicrobial agents and chemotherapy, 17(3), 455-460 (1980-03-01)
Prostaglandins enhanced the interferon response and therapeutic activity of interferon inducers in Friend leukemia virus-infected mice. A similar enhancement in interfron responsiveness but not antiviral activity was observed in mice infected with rapidly acute viruses.
M V Merritt et al.
Immunopharmacology, 5(1), 49-64 (1982-10-01)
We have used spin labeling, fluorescence polarization, and chemical analysis to characterize membrane properties of thymocytes from mice treated with immunomodulatory drugs. The number of thymocytes was reduced 90-95% by treatment of 6-9 week old mice with hydrocortisone acetate (HCA)
D A Stringfellow
Antimicrobial agents and chemotherapy, 11(6), 984-992 (1977-06-01)
2-Amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), polyinosinic acid-polycytidylic acid [poly(I:C)], and tilorone HCl induced high levels of serum interferon in mice. Each consequently protected mice against infection with several viruses. After daily injection of inducer, mice developed a reduced interferon response (hyporeactivity) to each
L S Anthony et al.
Clinical and investigative medicine. Medecine clinique et experimentale, 7(4), 343-348 (1984-01-01)
The modulation of murine host resistance to infection with Listeria monocytogenes by the substituted pyrimidine anti-viral compounds, 2-amino-5-bromo-6-methyl-4-pyrimidinol (ABMP), 2-amino-5-bromo-6-phenyl-4-pyrimidinol (ABPP) and 2-amino-5-iodo-6-phenyl-4-pyrimidinol (AIPP) was investigated. BAF1 mice given three daily injections of ABMP, ABPP (as well as of the
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service