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Sigma-Aldrich

Methyl 2-oxo-1-pyrrolidineacetate

96%

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About This Item

Empirical Formula (Hill Notation):
C7H11NO3
CAS Number:
Molecular Weight:
157.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

96%

refractive index

n20/D 1.472 (lit.)

density

1.131 g/mL at 25 °C (lit.)

SMILES string

COC(=O)CN1CCCC1=O

InChI

1S/C7H11NO3/c1-11-7(10)5-8-4-2-3-6(8)9/h2-5H2,1H3

InChI key

HPDZYDTXCOFUOY-UHFFFAOYSA-N

Application

Methyl 2-oxo-1-pyrrolidineacetate may be used in the synthesis of N-[(disubstituted-amino)alkyl]-2-oxo-1-pyrrolidineacetamide derivatives.

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup


Certificates of Analysis (COA)

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D E Butler et al.
Journal of medicinal chemistry, 27(5), 684-691 (1984-05-01)
A series of N-[(dialkylamino)alkyl]-2-oxo-1- pyrrolidineacetamides was synthesized. The title compounds reversed electroconvulsive shock (ECS) induced amnesia in mice when administered subsequent to the ECS treatment and were inactive in a general observational test for central nervous system (CNS) activity. Active

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