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Key Documents

164453

Sigma-Aldrich

2-Thiophenecarboxamide

99%

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About This Item

Empirical Formula (Hill Notation):
C5H5NOS
CAS Number:
Molecular Weight:
127.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

99%

mp

181-183 °C (lit.)

SMILES string

NC(=O)c1cccs1

InChI

1S/C5H5NOS/c6-5(7)4-2-1-3-8-4/h1-3H,(H2,6,7)

InChI key

DENPQNAWGQXKCU-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Hyunji Lee et al.
Journal of Korean medical science, 25(11), 1574-1581 (2010-11-10)
The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-κB) activity. The exact molecular mechanism by which microtubule rearrangement leads to NF-κB activation largely remains to be identified. However
Q Ren et al.
Translational psychiatry, 5, e666-e666 (2015-10-28)
Depression is a core symptom of methamphetamine (METH) withdrawal during the first several weeks of abstinence. However, the precise mechanisms underlying METH withdrawal symptoms remain unknown. Brain-derived neurotrophic factor (BDNF) and its specific receptor, tropomyosin-related kinase (TrkB), have a role
Yunfei Tan et al.
Pharmacology, biochemistry, and behavior, 188, 172839-172839 (2019-12-24)
The N-methyl-d-aspartate receptor (NMDAR) antagonists including phencyclidine (PCP) and ketamine produce cognitive deficits in rodents and humans. We previously reported that (R)-ketamine produced the beneficial effects compared to (S)-ketamine in several animal models including depression. Here we compared the effects
Rui Fu et al.
Neuroscience letters, 750, 135773-135773 (2021-02-28)
The mechanism underlying the high incidence of remifentanil-induced postoperative hyperalgesia is unclear. Also, no effective prevention method exists. Inflammatory pain-related studies showed that P2X4 purinergic receptors (P2X4Rs) in the dorsal horn of the spinal cord and dorsal root ganglia are
Tegan Triggs et al.
Expert opinion on investigational drugs, 29(5), 507-523 (2020-04-16)
Preterm birth is the leading cause of neonatal morbidity and mortality globally and poses a substantial economic burden. Consequently, there is a need for the identification of therapeutic targets and novel experimental drugs for the inhibition of preterm labor to

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