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Key Documents

162655

Sigma-Aldrich

D-Alanine

≥99%

Synonym(s):

(R)-2-Aminopropionic acid

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About This Item

Linear Formula:
CH3CH(NH2)CO2H
CAS Number:
Molecular Weight:
89.09
Beilstein/REAXYS Number:
1720249
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:

assay

≥99%

optical activity

[α]20/D −14.2°, c = 6 in 1 M HCl

optical purity

ee: 99% (GLC)

mp

291 °C (dec.) (lit.)

SMILES string

C[C@@H](N)C(O)=O

InChI

1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m1/s1

InChI key

QNAYBMKLOCPYGJ-UWTATZPHSA-N

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David Dodds et al.
mSphere, 5(3) (2020-06-12)
Using live microbes as therapeutic candidates is a strategy that has gained traction across multiple therapeutic areas. In the skin, commensal microorganisms play a crucial role in maintaining skin barrier function, homeostasis, and cutaneous immunity. Alterations of the homeostatic skin
A D'Aniello et al.
Brain research, 592(1-2), 44-48 (1992-10-02)
This report constitutes the first demonstration of the presence of D-alanine in the proteins of the human nervous system. Proteins of the frontal lobe white and gray matter of human brains, both normal and Alzheimer subjects, contain D-alanine at concentrations
G H Fisher et al.
Brain research bulletin, 26(6), 983-985 (1991-06-01)
In this report we present evidence for the presence of free D-aspartic acid (D-Asp) and D-alanine (D-Ala) in the white and gray matter of normal human brains and brains of individuals with Alzheimer's disease. D-Asp occurs at about the same
Y Nagata et al.
Experientia, 48(10), 986-988 (1992-10-15)
Twelve neutral free amino acids, i.e. serine, threonine, glutamine, asparagine, alanine, proline, methionine, tyrosine, valine, leucine, isoleucine and phenylalanine, were surveyed for the presence of D-enantiomers in plasma samples from patients with renal diseases and from normal subjects. D-serine, D-alanine
Kenji Hamase et al.
Biological & pharmaceutical bulletin, 28(9), 1578-1584 (2005-09-06)
The determination of small amounts of D-amino acids in mammalian tissues is still a challenging theme in the separation sciences. In this review, various gas-chromatographic and high-performance liquid chromatographic methods are discussed including highly selective and sensitive column-switching procedures. Based

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