162493

4-Fluorobenzylamine

97%

• Synonym(s): (4-Fluorophenyl)methanamine, 1-(4-Fluorophenyl)methanamine, 4-Fluorobenzenemethanamine, [(4-Fluorophenyl)methyl]amine, p-Fluorobenzylamine
• Linear Formula: FC₆H₄CH₂NH₂
• CAS Number: 140-75-0
• Molecular Weight: 125.14
• Beilstein/REAXYS Number: 636501
• EC Number: 205-430-4
• MDL number: MFCD00008120
• UNSPSC Code: 12352100
• eCl@ss: 39040409
• PubChem Substance ID: 24849984
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.512 (lit.)
• bp: 183 °C (lit.)
• density: 1.095 g/mL at 25 °C (lit.)
• functional group: amine; fluoro
• SMILES string: NCc1ccc(F)cc1
• InChI: 1S/C7H8FN/c8-7-3-1-6(5-9)2-4-7/h1-4H,5,9H2
• InChI key: IIFVWLUQBAIPMJ-UHFFFAOYSA-N
• Gene Information: human ... AOC3(8639) ; mouse ... Aoc3(11754)

Description

General description

[¹⁸F]4-fluorobenzylamine reacts with the α- and γ-carboxyl groups of folic acid to yield ¹⁸F-labeled folate. It is an important building block for the synthesis of ¹⁸F-labeled compounds.

Application

4-Fluorobenzylamine was used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H290,H314
• pcodes: P234 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 150.8 °F - closed cup
• flash_point_c: 66 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter