15149
N,N-Bis(phosphonomethyl)glycine
≥98.0% (T)
Synonym(s):
N-(Carboxymethyl)iminodi(methylphosphinic acid), Glyphosine
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$169.00
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10 G
$169.00
50 G
$567.00
About This Item
Empirical Formula (Hill Notation):
C4H11NO8P2
CAS Number:
Molecular Weight:
263.08
Beilstein/REAXYS Number:
1884944
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
assay
≥98.0% (T)
functional group
amine
carboxylic acid
SMILES string
O=P(CN(CP(O)(O)=O)CC(O)=O)(O)O
InChI
1S/C4H11NO8P2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
InChI key
OXHDYFKENBXUEM-UHFFFAOYSA-N
Related Categories
General description
N,N-Bis(phosphonomethyl)glycine was present in the ligand bound to human apotransferrin[1].
Application
Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89
Anti-diabetic; delay onset of diabetes in non-obese NOD mice
Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.†
Anti-diabetic; delay onset of diabetes in non-obese NOD mice
Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.†
Biochem/physiol Actions
Anti-diabetic; delay onset of diabetes in non-obese NOD mice[2]
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
8A - Combustible corrosive hazardous materials
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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