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144657

Sigma-Aldrich

Trifluoroacetamide

97%

Synonym(s):

2,2,2-Trifluoroacetamide

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About This Item

Linear Formula:
CF3CONH2
CAS Number:
Molecular Weight:
113.04
Beilstein/REAXYS Number:
1753625
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

form

solid

bp

162.5 °C (lit.)

mp

65-70 °C (lit.)

SMILES string

NC(=O)C(F)(F)F

InChI

1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7)

InChI key

NRKYWOKHZRQRJR-UHFFFAOYSA-N

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General description

Trifluoroacetamide is a good quencher of tryptophan fluorescence.

Application

Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Melody Anne de Laat et al.
PloS one, 13(6), e0200070-e0200070 (2018-06-30)
Hyperinsulinemia is a major risk factor for equine laminitis, a debilitating and painful foot condition. Sweet taste receptor (T1R2/3) inhibitors have been used to reduce the insulin and glucose responses to oral carbohydrates in other species. However, their effect in
P Midoux et al.
Biochimica et biophysica acta, 801(1), 16-25 (1984-09-07)
Trifluoroacetamide was found to be a good quencher of tryptophan fluorescence, and the quenching was shown to proceed via both a dynamic and a static process. The respective quenching constants were determined by the measurement of the decrease of the
Keita Tamura et al.
Plant & cell physiology, 58(5), 874-884 (2017-04-04)
The roots of Platycodon grandiflorus are widely used as a crude drug. The active components include a variety of triterpenoid saponins. Recent studies have revealed that Cyt P450 monooxygenases (P450s) function as triterpene oxidases in triterpenoid saponin biosynthesis in many
Chengquan Tan et al.
Scientific reports, 8(1), 10712-10712 (2018-07-18)
Sow milk contains necessary nutrients for piglets; however, the relationship between the levels of metabolites in sow milk and lactation performance has not been thoroughly elucidated to date. In this study, we analysed the metabolites in sow milk from Yorkshire
Simona Grasso et al.
Foods (Basel, Switzerland), 8(12) (2019-12-19)
The objective of this study was to develop a precise and accurate method to quantify cholesterol in turkey meat products using relative response factors, based on a modification of a previously published method for plant sterols determination. Validation was performed

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