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Key Documents

14452

Sigma-Aldrich

2-(4-Biphenylyl)-prop-2-yl 4′-methoxycarbonylphenyl carbonate

technical, ≥90% (HPLC)

Synonym(s):

BPOC reagent

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About This Item

Empirical Formula (Hill Notation):
C24H22O5
CAS Number:
Molecular Weight:
390.43
Beilstein/REAXYS Number:
2179522
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:

grade

technical

assay

≥90% (HPLC)

mp

90-100 °C (dec.)

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

COC(=O)c1ccc(OC(=O)OC(C)(C)c2ccc(cc2)-c3ccccc3)cc1

InChI

1S/C24H22O5/c1-24(2,20-13-9-18(10-14-20)17-7-5-4-6-8-17)29-23(26)28-21-15-11-19(12-16-21)22(25)27-3/h4-16H,1-3H3

InChI key

PXYPBZYXNPAGFW-UHFFFAOYSA-N

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Other Notes

For the introduction of the acid labile BPOC-amino protecting group[1]; Selective acidolytic cleavage of the BPOC-protection[2]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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[Selective cleavage of peptides in trifluoroethanol with acid-labile amino-protecting groups].
B Riniker et al.
Helvetica chimica acta, 58(4), 1086-1094 (1975-06-04)
Schnabel, E., et al.
Justus Liebigs Annalen der Chemie, 743, 69-69 (1971)

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