Journal of medicinal chemistry, 24(12), 1528-1531 (1981-12-01)
A number of nitrogen analogues of 9-[(2-hydroxyethoxy)methyl]guanine [acylovir, Zovirax] containing amine functions in the side chain were synthesized and tested for antiviral activity. These purine acyclic nucleosides were prepared by reaction of tris(trimethylsilyl)guanine or 2,6-diaminopurine sodium salt with the chloromethyl
Molluscicidal activity of synthetic derivatives of 2-hydroxyethylphthalimide.
J N Lopes et al.
Revista brasileira de biologia, 40(3), 635-637 (1980-08-01)
We report the design of reactive and hydrolytically degradable multilayers by the covalent layer-by-layer assembly of an azlactone-containing polymer, poly(2-vinyl-4,4-dimethylazlactone), with an acid-degradable, acetal-containing, small-molecule diamine linker. This approach yields cross-linked multilayers that contain (i) residual azlactone reactivity that can
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