135119
Triethyl phosphonoformate
98%
Synonym(s):
Ethyl diethoxyphospinylformate
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About This Item
Linear Formula:
(C2H5O)2P(O)COOC2H5
CAS Number:
Molecular Weight:
210.16
Beilstein/REAXYS Number:
1781949
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
assay
98%
refractive index
n20/D 1.423 (lit.)
bp
135 °C/12 mmHg (lit.)
density
1.11 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)P(=O)(OCC)OCC
InChI
1S/C7H15O5P/c1-4-10-7(8)13(9,11-5-2)12-6-3/h4-6H2,1-3H3
InChI key
NOJFJZZMRDSOLM-UHFFFAOYSA-N
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Phosphonoformate inhibits synthesis of Epstein-Barr virus (EBV) capsid antigen and transformation of human cord blood lymphocytes by EBV.
M Margalith et al.
Virology, 102(1), 226-230 (1980-04-15)
M Margalith et al.
Molecular and cellular biochemistry, 43(2), 97-103 (1982-03-19)
Three potential inhibitors of reverse transcriptase activities, phosphonoformate (PF), phosphonoacetate (PAA), and ethyl-diethyl phosphonoformate (Et-PF), were compared in this study. Only PF was found to inhibit the DNA polymerase activity of the purified reverse transcriptase of Moloney murine leukemia virus
Synthesis and antiviral properties of sterol phosphonoformates.
J M Bailey et al.
Biochemical Society transactions, 22(3), 353S-353S (1994-08-01)
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