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13450

Sigma-Aldrich

Benzylhydrazine oxalate salt

≥96.0%

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About This Item

Linear Formula:
C6H5CH2NHNH2 · (COOH)2
CAS Number:
Molecular Weight:
212.20
Beilstein/REAXYS Number:
3759765
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

≥96.0%

form

solid

mp

183-188 °C (dec.)

functional group

amine
carboxylic acid
hydrazine
phenyl

SMILES string

OC(=O)C(O)=O.NNCc1ccccc1

InChI

1S/C7H10N2.C2H2O4/c8-9-6-7-4-2-1-3-5-7;3-1(4)2(5)6/h1-5,9H,6,8H2;(H,3,4)(H,5,6)

InChI key

RCHUSXHCJLZTEY-UHFFFAOYSA-N

Application

Benzylhydrazine oxalate salt was used to study the reactions of bovine serum amine oxidase with benzylhydrazine.

Biochem/physiol Actions

Benzylhydrazine inhibits irreversibly human brain type A and type B monoamine oxidase.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Benzylhydrazine--a selective inhibitor of human and rat brain monoamine oxidase.
J A Roth
Biochemical pharmacology, 28(6), 729-732 (1979-03-15)
L Morpurgo et al.
The Biochemical journal, 260(1), 19-25 (1989-05-15)
Bovine serum amine oxidase is inhibited by benzylhydrazine (BHy), but recovers full activity after a few hours incubation [Hucko-Haas & Reed (1970) Biochem. Biophys. Res. Commun. 38, 396-400]. The first phase of the process, requiring about 15 min, was found

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