128724
7-Hydroxy-4-methylcoumarin
97%
Synonym(s):
4-MU, 4-Methylumbelliferone, Coumarin 4
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About This Item
Empirical Formula (Hill Notation):
C10H8O3 · H2O
CAS Number:
Molecular Weight:
194.18
Beilstein/REAXYS Number:
142217
EC Number:
MDL number:
UNSPSC Code:
12352103
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assay
97%
mp
188.5-190 °C (lit.)
λmax
≤221 nm
SMILES string
CC1=CC(=O)Oc2cc(O)ccc12
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Other Notes
This product has been replaced by M1381-ALDRICH | 4-Methylumbelliferone ≥98%
replaced by
Product No.
Description
Pricing
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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K Takagaki et al.
Journal of biochemical and biophysical methods, 19(2-3), 207-214 (1989-08-01)
The present paper describes a fluorometric assay for galactosaminoglycan-degrading endo-beta-xylosidase, utilizing glycosaminoglycan chains bearing a 4-methylumbelliferyl group at the reducing terminus as a substrate. This fluorogenic substrate is synthesized by human skin fibroblasts cultured in the presence of a fluorogenic
Yuan Shi et al.
Bioorganic & medicinal chemistry letters, 21(3), 956-960 (2011-01-11)
A series of new coumarin-based 1,2,4-triazole derivatives were designed, synthesized and evaluated for their antimicrobial activities in vitro against four Gram-positive bacteria (Staphylococcus aureus, MRSA, Bacillus subtilis and Micrococcus luteus), four Gram-negative bacteria (Escherichia coli, Proteus vulgaris, Salmonella typhi and
Sergio A Rodríguez et al.
Bioorganic & medicinal chemistry, 19(21), 6233-6238 (2011-10-04)
The antioxidant activity of 4-hydroxycoumarin synthetic derivatives and 4-methylumbelliferone were determined taking 4-hydroxycoumarin as the reference compound. Six 3-aryl-4-hydroxycoumarin derivatives were synthesized from 4-hydroxycoumarin as precursor in order to evaluate changes in their antioxidant properties due to C3-aryl substituent nature.
Laura Piccagli et al.
Bioorganic & medicinal chemistry, 18(23), 8341-8349 (2010-10-29)
In the present study, a structured-based virtual screening (VS) of differently substituted furocoumarins and analogues has been carried out against nuclear factor kappa B (NF-κB), with the objective of selecting molecules able to inhibit the binding of this transcription factor
Joanna Trykowska Konc et al.
European journal of medicinal chemistry, 46(6), 2252-2263 (2011-03-29)
A series of novel O-aminoalkyl substituted 7-hydroxycoumarins were synthesized and evaluated for antibacterial and anticancer toxicity. Two different synthetic procedures, conventional and microwave assisted were used, and the structures of the compounds were confirmed by IR, 1H, 13C NMR and
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