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127914

Sigma-Aldrich

1-Phenyl-3-pyrazolidinone

97%

Synonym(s):

Phenidone

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About This Item

Empirical Formula (Hill Notation):
C9H10N2O
CAS Number:
92-43-3
Molecular Weight:
162.19
Beilstein/REAXYS Number:
131856
EC Number:
202-155-1
MDL number:
MFCD00003094
UNSPSC Code:
12352100
PubChem Substance ID:
24847805
NACRES:
NA.22

assay

97%

form

powder

mp

119-121 °C (lit.)

SMILES string

O=C1CCN(N1)c2ccccc2

InChI

1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)

InChI key

CMCWWLVWPDLCRM-UHFFFAOYSA-N

Gene Information

rat ... Alox5(25290)

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Application

1-Phenyl-3-pyrazolidinone was used as a photograph developing agent.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

275.5 °F - Pensky-Martens closed cup

flash_point_c

135.3 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificates of Analysis (COA)

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The Oxidation of 1-Phenyl-4, 4-dimethyl-3-pyrazolidinone in Alkaline Solution.
The Journal of Organic Chemistry, 30(8), 2571-2575 (1965)
A Wakatsuki et al.
Biology of the neonate, 76(2), 84-91 (1999-07-08)
To determine whether ischemia followed by subsequent reperfusion can induce fetal cerebral oxidative damage, we created a model of fetal ischemia/reperfusion using rats at day 19 of pregnancy. Fetal ischemia was induced by unilateral occlusion of the utero-ovarian artery for
H C Kim et al.
Brain research, 874(1), 15-23 (2000-08-11)
Acculmulating evidence indicates that a marked generation of oxygen free radicals derived from the metabolism of arachidonic acid causes neurodegeneration. Recently, we have demonstrated that the novel antioxidant actions mediated by phenidone, a dual inhibitor of cyclooxygenase/lipoxygenase pathways, may play
Hasan Tunaz
Archives of insect biochemistry and physiology, 63(3), 93-100 (2006-10-19)
Influence of fungal species (conidia spores) on mortality of Pieris brassicae larvae differed when injected into the larvae. The effects of B. bassiana (ARSEF-1151) were expressed in a conidial dose-dependent manner on mortality of the larvae. An increased and faster
J C Bedick et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 130(1), 107-117 (2001-09-07)
Nodulation is the first, and qualitatively predominant, cellular defense reaction to bacterial infections in insects. We tested the hypothesis that eicosanoids also mediate nodulation reactions to bacterial challenge in adults of a social insect, the honey bee, Apis mellifera. Treating
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