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124753

Sigma-Aldrich

Succinamide

98%

Synonym(s):

Succinic diamide

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About This Item

Linear Formula:
NH2COCH2CH2CONH2
CAS Number:
110-14-5
Molecular Weight:
116.12
Beilstein/REAXYS Number:
1753983
EC Number:
203-739-9
MDL number:
MFCD00008042
UNSPSC Code:
12352100
PubChem Substance ID:
24847626
NACRES:
NA.22

assay

98%

mp

260-265 °C (dec.) (lit.)

solubility

cold water: soluble 220 part
boiling water: soluble 9 part
alcohol: insoluble
diethyl ether: insoluble

functional group

amide

SMILES string

NC(=O)CCC(N)=O

InChI

1S/C4H8N2O2/c5-3(7)1-2-4(6)8/h1-2H2,(H2,5,7)(H2,6,8)

InChI key

SNCZNSNPXMPCGN-UHFFFAOYSA-N

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Application

Succinamide has been used in the characterization of a novel biuret hydrolase from the cysteine hydrolase superfamily. It was used as nitrogen supplement in the culture medium of Scenedesmus obliquus and green algae.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW2277
MKCM6562
MKCM6466
MKCH5636

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Eight new [2]rotaxanes have been prepared, incorporating an alpha-cyclodextrin as the rotor, a stilbene as the axle, and trinitrophenyl substituents as capping groups. Strategies have been devised to elaborate these by linking the rotor to the axle, to produce two
T Watanabe et al.
Chemical & pharmaceutical bulletin, 45(9), 1458-1469 (1997-10-23)
A series of succinamide derivatives containing the 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one skeleton (6a-z) was prepared and evaluated for binding affinity to muscarinic receptors in vitro and for antagonism of bradycardia and salivation in vivo in comparison with AF-DX 116 (1a). Structure-activity relationships (SAR)
Petras P Dzeja et al.
American journal of physiology. Heart and circulatory physiology, 284(4), H1048-H1056 (2003-04-02)
Modulation of mitochondrial respiratory chain, dehydrogenase, and nucleotide-metabolizing enzyme activities is fundamental to cellular protection. Here, we demonstrate that the potassium channel opener diazoxide, within its cardioprotective concentration range, modulated the activity of flavin adenine dinucleotide-dependent succinate dehydrogenase with an
Birgit T Priest et al.
Biochemistry, 43(30), 9866-9876 (2004-07-28)
Sodium channel blockers are used clinically to treat a number of neuropathic pain conditions, but more potent and selective agents should improve on the therapeutic index of currently used drugs. In a high-throughput functional assay, a novel sodium channel (Na(V))
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