122432
4-Amino-1-naphthalenecarbonitrile
97%
Synonym(s):
4-Cyano-1-naphthylamine
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About This Item
Linear Formula:
H2NC10H6CN
CAS Number:
Molecular Weight:
168.19
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
97%
form
solid
mp
174.5-176.5 °C (lit.)
SMILES string
Nc1ccc(C#N)c2ccccc12
InChI
1S/C11H8N2/c12-7-8-5-6-11(13)10-4-2-1-3-9(8)10/h1-6H,13H2
InChI key
LUSIZUFVMKYWGX-UHFFFAOYSA-N
General description
4-Amino-1-naphthalenecarbonitrile on hydrolysis yields 4-amino-1-naphthoic acid.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Y Qian et al.
Bioorganic & medicinal chemistry, 7(12), 3011-3024 (2000-02-05)
Cysteine farnesylation at the carboxylate terminal tetrapeptide CAAX of Ras protein is catalyzed by farnesyltransferase. This lipid modification is necessary for regulatory function of both normal and oncogenic Ras. The high frequency of Ras mutation in human cancers has prompted
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