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Sigma-Aldrich

Pyridoxine hydrochloride

98%

Synonym(s):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C8H11NO3 · HCl
CAS Number:
58-56-0
Molecular Weight:
205.64
Beilstein/REAXYS Number:
3632435
EC Number:
200-386-2
MDL number:
MFCD00012807
UNSPSC Code:
12352005
PubChem Substance ID:
329749347

assay

98%

form

powder

color

white to off-white

mp

214-215 °C (lit.)

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

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General description

Pyridoxine hydrochloride is a water soluble vitamin. It is available through dietary sources like, meat, fish, nuts, vegetables and fruits.

Biochem/physiol Actions

Pyridoxine/vitamin B6 is implicated in cellular metabolism, fatty acid biosynthesis, amino acid biosynthesis and catabolism. It is also implicated in the production of neurotransmitters, chlorophyll and plant hormones. Pyridoxine acts as a cofactor for several biochemical reactions. Pyridoxine deficiency is associated with peripheral neuropathy. Pyridoxine hydrochloride is available in parenteral and oral formulations.

Certificates of Analysis (COA)

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Journal of clinical pharmacology, 53(3), 334-338 (2013-02-28)
Although Diclectin (doxylamine/pyridoxine delayed-released combination) is widely used in Canada, its pharmacokinetics (PK) during pregnancy has never been described. The objective of this study was to compare the PK of doxylamine/pyridoxine delayed-released combination in pregnant versus nonpregnant women. The apparent
Sonia Fargue et al.
Biochimica et biophysica acta, 1832(10), 1776-1783 (2013-04-20)
Primary hyperoxaluria type 1 (PH1) is a rare hereditary calcium oxalate kidney stone disease caused by a deficiency of the liver-specific pyridoxal-phosphate-dependent peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT). About one third of patients are responsive to pharmacological doses of pyridoxine (vitamin
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