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112372

Sigma-Aldrich

Ethyl cinnamate

99%

Synonym(s):

3-Phenyl-2-propenoic acid ethyl ester, Ethyl 3-phenyl-2-propenoate, NSC 6773

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About This Item

Linear Formula:
C6H5CH=CHCOOC2H5
CAS Number:
103-36-6
Molecular Weight:
176.21
Beilstein/REAXYS Number:
775541
EC Number:
203-104-6
MDL number:
MFCD00009189
UNSPSC Code:
12352100
PubChem Substance ID:
24847091
NACRES:
NA.22

Quality Level

100

assay

99%

impurities

may contain alpha-tocopherol (synthetic)

refractive index

n20/D 1.558 (lit.)

bp

271 °C (lit.)

mp

6-8 °C (lit.)

density

1.049 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOC(=O)\C=C\c1ccccc1

InChI

1S/C11H12O2/c1-2-13-11(12)9-8-10-6-4-3-5-7-10/h3-9H,2H2,1H3/b9-8+

InChI key

KBEBGUQPQBELIU-CMDGGOBGSA-N

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Application

  • Antimicrobial and antiproliferative effects: Essential oils including Ethyl cinnamate derived from Zingiberaceae family show promising antimicrobial and antiproliferative properties, suggesting their potential application in oral healthcare products. This study provides insight into the utilization of natural products for medical and pharmaceutical applications (Amil et al., 2024).
  • Biodistribution and cellular interactions in medical research: Ethyl cinnamate could be investigated for its role in enhancing the permeability and imaging contrast in studies like those investigating the biodistribution of intravenously delivered mesenchymal stromal cells. Such applications could improve understanding in cellular therapies and regenerative medicine (Pichardo et al., 2022).

Biochem/physiol Actions

Ethyl cinnamate inhibits the growth of Chlorella pyrenoidosa.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB1621
STBL4204
STBL3440
STBL1830
STBL2297

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Gessica D Gonçalves et al.
Anatomical record (Hoboken, N.J. : 2007), 303(10), 2668-2678 (2020-01-28)
Fetal hypoxia is a common complication of pregnancy. We have previously reported that maternal hypoxia in late gestation in mice gives rise to male offspring with reduced nephron number, while females have normal nephron number. Male offspring later develop proteinuria
Li-Li Gao et al.
Huan jing ke xue= Huanjing kexue, 34(1), 156-162 (2013-03-16)
The effects of ethyl cinnamate on the growth and physiological characteristics of Chlorella pyrenoidosa were studied. The allelopathic mechanisms were explored, from views of chlorophyll a content, antioxidant enzyme activities, reactive oxygen species (ROS) level, malondialdehyde (MDA) content and photosynthetic
Nam-Jin Kim et al.
Pest management science, 64(8), 857-862 (2008-03-08)
This study was aimed at assessing the toxicity of ethyl cinnamate and ethyl p-methoxycinnamate (EMC) identified in Kaempferia galangal L. (Zingiberaceae) rhizome and another 12 known compounds to third-instar larvae from laboratory-reared Culex pipiens pallens Forskal, Aedes aegypti L. and
Rozana Othman et al.
Planta medica, 68(7), 655-657 (2002-07-27)
From the rhizomes of Kaempferia galanga, ethyl cinnamate (EC) was isolated and its vasorelaxant effect was examined on the rat aorta. EC inhibited the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50
Victor G Puelles et al.
Kidney international, 96(2), 505-516 (2019-06-04)
Recent developments in optical tissue clearing have been difficult to apply for the morphometric analysis of organs with high cellular content and small functional structures, such as the kidney. Here, we establish combinations of genetic and immuno-labelling for single cell
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