109924

3-Hydroxypropionitrile

97%

• Synonym(s): 2-Cyanoethanol, Ethylene cyanohydrin, Hydracrylonitrile
• Linear Formula: HOCH₂CH₂CN
• CAS Number: 109-78-4
• Molecular Weight: 71.08
• Beilstein/REAXYS Number: 635773
• MDL number: MFCD00002826
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846946
• NACRES: NA.22

Properties

• vapor density: 2.5 (vs air)
• vapor pressure: <0.1 mmHg ( 20 °C)
• assay: 97%
• autoignition temp.: 922 °F
• expl. lim.: 12.1 %
• refractive index: n20/D 1.425 (lit.)
• bp: 228 °C (lit.)
• mp: −46 °C (lit.)
• density: 1.04 g/mL at 25 °C (lit.)
• functional group: hydroxyl; nitrile
• SMILES string: OCCC#N
• InChI: 1S/C3H5NO/c4-2-1-3-5/h5H,1,3H2
• InChI key: WSGYTJNNHPZFKR-UHFFFAOYSA-N

Description

General description

3-Hydroxypropionitrile, at low 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) surface excesses, has the phospholipid oriented with the polar headgroups pointing out of the solution.

3-Hydroxypropionitrile serves as an intermediate through nucleophilic addition or hydrogenation to synthesize heterocyclic rings, mercaptopropanoic acid, or cyclophosphamide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 235.4 °F - closed cup
• flash_point_c: 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter