Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

107263

Sigma-Aldrich

5-Hydroxy-2-methylpyridine

99%

Synonym(s):

6-Methyl-3-pyridinol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H7NO
CAS Number:
1121-78-4
Molecular Weight:
109.13
EC Number:
214-337-8
MDL number:
MFCD00006339
UNSPSC Code:
12352100
PubChem Substance ID:
24846760
NACRES:
NA.22

Quality Level

200

assay

99%

form

solid

mp

168-170 °C (lit.)

solubility

dichloromethane: soluble

SMILES string

Cc1ccc(O)cn1

InChI

1S/C6H7NO/c1-5-2-3-6(8)4-7-5/h2-4,8H,1H3

InChI key

DHLUJPLHLZJUBW-UHFFFAOYSA-N

Application

  • 5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
  • It was used in synthesis of [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2].
  • It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels.
  • It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBF9625V
BCBF3821V
BCBF4770V
BCBF0251V
1442720

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Margaret E Welk et al.
Inorganic chemistry, 41(20), 5119-5125 (2002-10-02)
Electronic effects and the bond network are the two factors that cause out-of-center distortions in octahedral d(0) transition metal oxide fluoride anions. Overlap between filled oxide p orbitals and vacant cation d orbitals results in strong, short metal-oxide bonds causing
Tetrahedron Asymmetry, 17, 1728-1728 (2006)
Synthesis of (R)-(+)-methyl 3-amino-3-(5-hydroxy-2-pyridinyl) propanoate, an analog of l-azatyrosine.
Adamczy M and Reddy RE.
Tetrahedron Asymmetry, 12(7), 1047-1054 (2001)
Douglas S Williams et al.
Inorganic chemistry, 46(8), 2944-2946 (2007-03-23)
A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3alpha).
Jonita Stankevičiūtė et al.
Scientific reports, 6, 39129-39129 (2016-12-17)
Pyridinols and pyridinamines are important intermediates with many applications in chemical industry. The pyridine derivatives are in great demand as synthons for pharmaceutical products. Moreover, pyridines are used either as biologically active substances or as building blocks for polymers with

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service